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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPD1
All Species:
45.45
Human Site:
T547
Identified Species:
66.67
UniProt:
P10809
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10809
NP_002147.2
573
61055
T547
T
T
A
E
V
V
V
T
E
I
P
K
E
E
K
Chimpanzee
Pan troglodytes
XP_001169030
573
61022
T547
T
T
A
E
V
V
V
T
E
I
P
K
E
E
K
Rhesus Macaque
Macaca mulatta
XP_001082397
576
61283
T547
T
T
A
E
V
V
V
T
E
I
P
K
E
E
K
Dog
Lupus familis
XP_536016
573
60977
T547
T
T
A
E
V
V
V
T
E
I
P
K
E
E
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_034607
573
60937
T547
T
T
A
E
A
V
V
T
E
I
P
K
E
E
K
Rat
Rattus norvegicus
P63039
573
60937
T547
T
T
A
E
A
V
V
T
E
I
P
K
E
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL72
573
60954
T547
S
T
A
E
A
V
V
T
E
V
P
K
E
E
K
Frog
Xenopus laevis
NP_001083970
579
61616
T547
T
T
A
E
A
V
V
T
E
I
P
K
E
E
K
Zebra Danio
Brachydanio rerio
NP_851847
575
61178
T547
S
T
A
E
A
V
V
T
E
I
P
K
E
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02649
573
60790
T543
T
T
A
E
A
V
V
T
E
I
P
K
E
D
G
Honey Bee
Apis mellifera
XP_392899
570
60394
A540
T
T
A
E
A
V
V
A
E
L
P
K
E
E
P
Nematode Worm
Caenorhab. elegans
P50140
568
60082
T539
A
T
T
E
C
V
V
T
E
I
P
K
E
E
A
Sea Urchin
Strong. purpuratus
XP_795205
586
62222
T553
T
T
A
E
A
V
I
T
E
T
P
K
E
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43298
576
60917
V556
T
T
T
E
S
I
I
V
E
I
P
K
E
E
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P29197
577
61262
V553
T
T
T
E
A
V
V
V
D
L
P
K
D
E
S
Baker's Yeast
Sacchar. cerevisiae
P19882
572
60733
V547
A
T
T
E
V
A
I
V
D
A
P
E
P
P
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
98
N.A.
97.5
97.5
N.A.
N.A.
94
89.4
87.3
N.A.
74
74.6
71
74.9
Protein Similarity:
100
100
98.7
98.9
N.A.
98.2
98.2
N.A.
N.A.
97.7
94.9
94.4
N.A.
86.3
86
82.3
87.3
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
80
93.3
86.6
N.A.
80
73.3
73.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
86.6
80
73.3
73.3
Percent
Protein Identity:
N.A.
58.3
N.A.
57.8
55.6
N.A.
Protein Similarity:
N.A.
76.9
N.A.
76.4
73.3
N.A.
P-Site Identity:
N.A.
60
N.A.
53.3
26.6
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
73.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
75
0
57
7
0
7
0
7
0
0
0
0
19
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
13
0
0
0
7
7
0
% D
% Glu:
0
0
0
100
0
0
0
0
88
0
0
7
88
82
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
19
0
0
69
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
94
0
0
57
% K
% Leu:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
100
0
7
7
13
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% S
% Thr:
75
100
25
0
0
0
0
75
0
7
0
0
0
7
0
% T
% Val:
0
0
0
0
32
88
82
19
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _